PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
|Lot:||Please refer to product vial|
|Immunogen:||Recombinant protein of human PD-1|
|Synonyms:||PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l|
|Calculated MW:||32 kDa|
|Observed MW:||Refer to figure|
|Applications:||WB, IHC, FC|
WB: 1:500 – 1:2000
|Purification Method:||Affinity purified|
|Buffer:||PBS with 0.02% sodium azide, 50% glycerol, pH7.3|
|Storage Conditions:||Store at -20°C. Avoid freeze / thaw cycles.|
FOR RESEARCH USE ONLY. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.