GITR (TNFRSF18, tumor necrossis factor receptor superfamily member 18) is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. This anti-mouse GITR antibody was developed from rat immunization, and expressed in adherent culture of rat hybridoma clone CB38.
|Lot:||Please refer to product vial|
|Immunogen:||Mouse GITR, ECD domain|
|Synonyms:||TNFRSF18, CD357, Gitr|
ELISA: 0.2-1.0 ug/mL, FACS: 1-5 ug/mL
|QC:||Endotoxin level: <2 EU/mg by the LAL method, Purity: >90% by SDS-PAGE|
|Production Method:||Expressed from rat hybridoma clone CB38|
|Purification Method:||Affinity purified|
|Buffer:||PBS, pH 7.4|
|Storage Conditions:||Store at -20°C. Avoid freeze / thaw cycles. Stable for 12 months from date of purchase when stored as recommended.|
FOR RESEARCH USE ONLY. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
100 ug - $325.00 – $485.00