ICOSLG is ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
This ICOSLG antibody was developed from mouse immunization, and expressed in suspension culture of mouse hybridoma clone CB31.
|Lot:||Please refer to product vial|
|Immunogen:||Human ICOSLG, ECD domain|
|Synonyms:||ICOS ligand, B7 homolog2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, CD275, ICOSL, KIAA0653|
ELISA: 0.2-1.0 ug/mL, FACS: 1-5 ug/mL
|QC:||Endotoxin level: <2 EU/mg by the LAL method, Purity: >90% by SDS-PAGE|
|Production Method:||Expressed from mouse hybridoma clone CB31|
|Purification Method:||Affinity purified|
|Buffer:||PBS, pH 7.4|
|Storage Conditions:||Store at -20°C. Avoid freeze / thaw cycles. Stable for 12 months from date of purchase when stored as recommended.|
FOR RESEARCH USE ONLY. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
100 ug - $325.00 – $485.00