Anti-transferrin receptor may be used to identify activated lymphocytes. The CD71 antibody may be used in studies of erythropoiesis.
|Ig Subclass||Mouse IgG1|
Mouse Anti-Human CD71 (Clone T56/14) recognizes Human CD71 transferrin receptor (Mr 190 kDa). The transferrin receptor is a cell surface glycoprotein related to cell proliferation. Up-regulation of the CD71 antigen is associated with actively dividing cells. Transferrin receptors are also present on reticulocytes, but are lost during maturation into erythrocytes.
|Buffer||0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.|
|Alternate Names||Transferrin Receptor|
|Purification Method||Affinity Purified|
|Reporter Molecule||Fluorescein (FITC) is a small fluorescent organic molecule with a molecular weight of 473 daltons with an absorbance maximum of ~492 nm and an emission maximum of ~518 nm.|
|Dilution||Each investigator should determine their own optimal working dilution for specific applications.|
1. Trowbridge, S. I. et al. (1981) Proc. Nat’l. Acad. Sci. 78:3039
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