CrownBio now offers genomic DNA (gDNA) reference standards, which represent biologically-relevant controls that can be directly incorporated into your sample processing workflows in order to optimize your protocols, evaluate assay sensitivity and specificity, and analyze the impact of workflow changes on downstream analysis. They represent ideal materials for both assay development and routine monitoring of assay performance.

These genomic DNA reference standards are derived from isogenic mutation cell lines with many recurrent pathway-activating mutations in various genes based on data from the Sanger Institute’s COSMIC database.

Name Catalog # Price  

APC E1309fs*4 Genomic DNA

C6146G

APC R213* Genomic DNA

C6150G

BRAF V600D Genomic DNA

C6048G

BRAF V600E Genomic DNA (c.1799_1800TG>AA)

C6046G

BRAF V600E Genomic DNA (c.1799T>A)

C6047G

BRAF V600G Genomic DNA

C6050G

BRAF V600K Genomic DNA

C6044G

BRAF V600M Genomic DNA

C6049G

BRAF V600R Genomic DNA

C6045G

BRCA1 E1161Fs Genomic DNA

C6112G

BRCA1 E23fs*17 Genomic DNA

C6107G

BRCA1 Q1756fs*74 Genomic DNA

C6108G

CTNNB1 S33C Genomic DNA

C6139G

CTNNB1 S33Y Genomic DNA

C6140G

CTNNB1 S45del Genomic DNA

C6143G

EGFR c.2310_2311insGGT p.D770_N771insG Genomic DNA

C6027G

EGFR c.2319_2320insCAC p.H773_V774insH Genomic DNA

C6028G

EGFR C797S/T790M Genomic DNA (c.2389T>A)

C6177G

EGFR C797S/T790M Genomic DNA (c.2390G>C)

C6176G

EGFR E746_A750del Genomic DNA (c.2236_2250del15)

C6017G

EGFR E746_A750>IP Genomic DNA

C6024G

EGFR E746_S752>A Genomic DNA

C6007G

EGFR E746_S752>D Genomic DNA

C6005G

EGFR E746_S752>V Genomic DNA

C6008G

EGFR E746_T751>A Genomic DNA

C6010G

EGFR E746_T751del Genomic DNA

C6009G

EGFR E746_T751>I Genomic DNA

C6014G

EGFR E746_T751>V Genomic DNA

C6013G

EGFR E746_A750del Genomic DNA (c.2235_2249del15)

C6016G

EGFR G719A Genomic DNA

C6002G

EGFR G719C Genomic DNA

C6001G

EGFR G719S Genomic DNA

C6000G

EGFR K745_E749del Genomic DNA

C6015G

EGFR L747_A750>P Genomic DNA (c.2238_2248>GC)

C6022G

EGFR L747_A750>P Genomic DNA (c.2239_2248TTAAGAGAAG>C)

C6021G

EGFR L747_E749del Genomic DNA

C6023G

EGFR L747_P753>Q Genomic DNA

C6006G

EGFR L747_P753>S Genomic DNA

C6004G

EGFR L747_S752del Genomic DNA

C6003G

EGFR L747_T751del Genomic DNA (c.2239_2253del15)

C6011G

EGFR L747_T751del Genomic DNA (c.2240_2254del15)

C6012G

EGFR L747_T751>P Genomic DNA

C6018G

EGFR L747_T751>Q Genomic DNA

C6020G

EGFR L747_T751>S Genomic DNA

C6019G

EGFR L858R Genomic DNA

C6030G

EGFR L861Q Genomic DNA

C6031G

EGFR Q787R Genomic DNA

C6182G

EGFR S768I Genomic DNA

C6025G

EGFR T790M Genomic DNA

C6029G

EGFR V769_D770insASV Genomic DNA

C6026G

EGFR V843I Genomic DNA

C6185G

ESR1 D538G Genomic DNA

C6169G

ESR1 Y537C Genomic DNA

C6172G

ESR1 Y537N Genomic DNA

C6171G

ESR1 Y537S Genomic DNA

C6170G

FLT3 D835H Genomic DNA

C6154G

FLT3 I836delI Genomic DNA

C6157G

HCT116 Genomic DNA (Wild Type)

C6052G-WT

HRAS G13R Genomic DNA

C6078G

HRAS Q61K Genomic DNA

C6079G

HRAS Q61R Genomic DNA

C6080G

IDH2 R140L Genomic DNA

C6227G

IDH2 R140Q Genomic DNA

C6225G

IDH2 R140W Genomic DNA

C6226G

IDH2 R172G Genomic DNA

C6232G

IDH2 R172K Genomic DNA

C6228G

IDH2 R172M Genomic DNA

C6229G

IDH2 R172S Genomic DNA

C6230G

IDH2 R172W Genomic DNA

C6231G

KRAS G12A Genomic DNA

C6037G

KRAS G12C Genomic DNA

C6032G

KRAS G12D Genomic DNA

C6036G

KRAS G12R Genomic DNA

C6034G

KRAS G12S Genomic DNA

C6033G

KRAS G12V Genomic DNA

C6035G

KRAS G13A Genomic DNA

C6042G

KRAS G13C Genomic DNA

C6038G

KRAS G13D Genomic DNA

C6041G

KRAS G13R Genomic DNA

C6040G

KRAS G13S Genomic DNA

C6039G

KRAS G13V Genomic DNA

C6043G

KRAS Q61H Genomic DNA

C6062G

NRAS E62fs*6 Genomic DNA

C6200G

NRAS G12C Genomic DNA

C6067G

NRAS G12D Genomic DNA

C6065G

NRAS G12S Genomic DNA

C6066G

NRAS G13R Genomic DNA

C6069G

NRAS Q61K Genomic DNA

C6072G

NRAS Q61R Genomic DNA (c.182A>G)

C6071G

NRAS Q61R Genomic DNA (c.182A>T)

C6073G

PIK3CA C420R Genomic DNA

C6060G

PIK3CA E542K Genomic DNA

C6053G

PIK3CA E545G Genomic DNA

C6055G

PIK3CA E545K Genomic DNA

C6054G

PIK3CA G13V Genomic DNA

C6070G

PIK3CA H1047L Genomic DNA

C6052G

PIK3CA H1047R Genomic DNA

C6051G

PIK3CA Q546K Genomic DNA

C6057G

PTEN R130G Genomic DNA

C6127G

PTEN R130Q Genomic DNA

C6128G

PTEN R233* Genomic DNA

C6133G

RKO Genomic DNA (Wild Type)

C6051G-WT

TP53 C242Y Genomic DNA

C6086G

TP53 D281G Genomic DNA

C6101G

TP53 G245C Genomic DNA

C6090G

TP53 G245D Genomic DNA

C6088G

TP53 G245S Genomic DNA

C6087G

TP53 G245V Genomic DNA

C6089G

TP53 R158C Genomic DNA

C6193G

TP53 R158G Genomic DNA

C6194G

TP53 R248L Genomic DNA

C6093G

TP53 R248Q Genomic DNA

C6091G

TP53 R248W Genomic DNA

C6092G

TP53 R273C Genomic DNA

C6099G

TP53 R273H Genomic DNA

C6098G

TP53 R282G Genomic DNA

C6103G

TP53 R282Q Genomic DNA

C6104G